Chicago Sports Fan... Nephrologist by day. My tweets are not medical advice. The views expressed here are my own and not those of my employerhttps://connect.medsky.network/profile/edgarvlermamd.medsky.networkhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mykdcsa2x222Among patients w/ IgA nephropathy #IgAN, treatment w/ sibeprenlimab stabilized the eGFR slope over 24 months, consistent w/ a reduced risk of kidney-function decline ca. 2026 from @nejm.org #Nephpearls #KidneyWk #NephSky Visual Abstract by @cristinapopa.bsky.social 👉 https://www.nejm.org/doi/full/10.1056/NEJMoa2609127?query=featured_nephrology23 Oct 2026 13:54 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mykdcsa2x222https://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3myivnunwck22Diagnosis of ADPKD remains radiological/ clinical in most cases #Nephpearls #KidneyWk #NephSky 👉 pubmed.ncbi.nlm.nih.gov/40126492/23 Oct 2026 00:17 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3myivnunwck22https://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3myit2e47xs22Trends in Mortality of Patients with Central Venous Catheters (CVC) vs Arteriovenous (AV) Accesses for Hemodialysis ca. 2026 from @asnpublications.bsky.social #Nephpearls #VascularAccessPearls #KidneyWk #NephSky 👉 https://journals.lww.com/jasn/fulltext/10.1681/asn.0000001293~trends-in-mortality-of-patients-with-central-venous22 Oct 2026 23:30 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3myit2e47xs22https://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3myga7gairc2sGoing Beyond Survival: Kidney Transplantation in the Older Population ca. 2026 from @asnpublications.bsky.social #Nephpearls #KidneyWk #NephSky 👉 https://www.kidneynews.org/view/journals/kidney-news/18/10/11/article-p41_42.xml 👉 pubmed.ncbi.nlm.nih.gov/42173346/21 Oct 2026 22:48 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3myga7gairc2shttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3myfghvucus2uSECONDS checklist for the interpretation of kidney ultrasound #Nephpearls #NephSecrets #NephSky 👉 https://www.us.elsevierhealth.com/nephrology-secrets-9780443121746.html?srsltid=AU7gw4UgQNwsb2T3YkumF0gtlP_hGvUpSugXIC9w9544GsKDNL4R5DP521 Oct 2026 15:07 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3myfghvucus2uhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3myfew657zk2uPoint-of-care ultrasound #POCUS training in #nephrology: a position statement by the International Alliance for POCUS in Nephrology ca. 2024 from @nephrothaniel.bsky.social @myadla.bsky.social #Nephpearls #KidneyWk #NephSky 👉 pubmed.ncbi.nlm.nih.gov/39502372/21 Oct 2026 14:39 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3myfew657zk2uhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3myenkfgqss2uMore GDMT ≠ zero trade-offs #Nephpearls #KidneyWk #NephSky ⚠️ In CKM, optimizing therapy can also mean navigating a higher risk of hyperkalemia ✅ The goal isn’t to back off - it’s to monitor, manage, and keep patients on the therapies that change outcomes 👉 pubmed.ncbi.nlm.nih.gov/42265997/21 Oct 2026 07:41 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3myenkfgqss2uhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3myafpbxzqs2bVascular endothelial growth factor inhibitor (VEGFi) induced hypertension ca. 2026 from @akdhjournal.bsky.social @gudnephron.bsky.social @sabinekaram.bsky.social @priti899.bsky.social #Nephpearls #OncoNephrology 🦀 #NephSky 👉 pubmed.ncbi.nlm.nih.gov/42405920/19 Oct 2026 15:10 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3myafpbxzqs2bhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mya6tddncc2bPrimary Aldosteronism and the Kidneys ca. 2026 from @akdhjournal.bsky.social @hswapnil.medsky.social #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/42397322/19 Oct 2026 13:07 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mya6tddncc2bhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mxw7kgfqp22uIf you're coming to @asnkidney.bsky.social #KidneyWk do not miss this session "Too Many Therapies for Diabetic Kidney Disease: What a Great Problem to Have!" #Nephpearls #NephSky 🗓️ 25 Oct ⏰ 9:30 AM MDT 📍 Four Seasons Ballroom 1, Convention Center 👉 https://asn-online.org/education/kidneyweek/2026/program-session-details.aspx?sessId=53332815 Oct 2026 13:53 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mxw7kgfqp22uhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mxkwzkv7is2nApproach to hematuria ca. 2026 from @ajkd.bsky.social #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/42767705/11 Oct 2026 02:22 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mxkwzkv7is2nhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mxjibtblns2sPRO/CON debate: nonsteroidal (finerenone) vs. steroidal (spironolactone/ eplerenone) mineralocorticoid receptor antagonists in CKD: progress, pragmatism, and remaining uncertainties ca. 2026 from @ckj-era.bsky.social #Nephpearls #Cardiorenal #NephSky 👉 pubmed.ncbi.nlm.nih.gov/42682722/10 Oct 2026 12:25 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mxjibtblns2shttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mxbyhet5xs2rC3G Glomerulopathy: Mechanistic Targets 🎯 of Potential Novel Therapies from @kdigo.org #Nephpearls #NephSky 👉 kdigo.org/infographics/07 Oct 2026 12:53 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mxbyhet5xs2rhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mxbxr56zxk2rIgA Nephropathy #IgAN: Pathophysiology and Mechanistic Targets 🎯 of Potential Novel Therapies from @kdigo.org #Nephpearls #NephSky 👉 kdigo.org/infographics/07 Oct 2026 12:41 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mxbxr56zxk2rhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mx2ugcgwss2rSepsis is a syndrome defined by organ dysfunction because of a dysregulated host response to infection #Nephpearls #AKIinICU #NephSky 📌 Septic shock is a subset of sepsis defined by hypotension requiring vasopressors to maintain an MAP >/= 65 mm Hg and serum lactate >2 mmol/L after resuscitation04 Oct 2026 16:52 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mx2ugcgwss2rhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mwwnijgmfs2oTreatment with maximally tolerated RAASi alone does not sufficiently slow the rate of eGFR decline in high-risk patients with IgA nephropathy #IgAN, leaving patients at risk of ESKD ca. 2026 from @asnpublications.bsky.social #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/42584957/03 Oct 2026 00:38 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mwwnijgmfs2ohttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mwrhbtgx722gClinical conditions related to LVADs that may arise during hemodialysis #Nephpearls #NephSky 👉 https://link.springer.com/book/10.1007/978-3-319-74657-930 Sep 2026 23:03 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mwrhbtgx722ghttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mwrg7avybs24Call 📢 for papers: "The Jerry Yee: Clinical Challenges in Diagnosis and Treatment in Nephrology" #Nephpearls #NephSky 🗓️ Deadline for submissions: 15 October 2026 👉 https://www.sciencedirect.com/special-issue/336669/the-jerry-yee-clinical-challenges-in-diagnosis-and-treatment-in-nephrology30 Sep 2026 22:44 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mwrg7avybs24https://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mwpykrhtj22cImpact of proteinuria levels on long-term kidney outcomes in IgA nephropathy: a meta-analysis ca. 2026 from @glomcon.org Rare Kidney Disease journal #Nephpearls #NephSky 👉🏼 https://link.springer.com/article/10.1007/s44531-026-00005-330 Sep 2026 09:07 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mwpykrhtj22chttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mwpwzit56k2zTen tips for the diagnosis and management of nephrotic syndrome ca. 2026 #Nephpearls #NephSky 👉🏼 pubmed.ncbi.nlm.nih.gov/42707999/30 Sep 2026 08:40 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mwpwzit56k2zhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mwhbth4lvs2wClassic course of whole-kidney GFR and UAE according to the natural (proteinuric) pathway of #Diabetic #Kidney Disease (DKD) ca. 2017 #Nephpearls #NephSky 👉🏼 pubmed.ncbi.nlm.nih.gov/28143897/26 Sep 2026 21:59 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mwhbth4lvs2whttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mwgxiemdk22lAdults with #IgAN are at greater risk of adverse kidney outcomes versus nonglomerular CKD and substantially higher risks of heart failure and death compared with no CKD ca. 2026 from @KIReports #Nephpearls #RKDSummit #NephSky 👉🏼 pubmed.ncbi.nlm.nih.gov/42027552/26 Sep 2026 18:54 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mwgxiemdk22lhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mwgwuvsats2uNot all #IgAN therapies are created equal #Nephpearls #RKDSummit #NephSky 👉🏼 pubmed.ncbi.nlm.nih.gov/40928891/26 Sep 2026 18:43 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mwgwuvsats2uhttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mwgw23swjs23Dipstick hemoglobinuria is associated with histologic markers of active disease in #IgAN and may provide clinically relevant information to complement current assessment of disease activity in #IgAN ca. 2026 #Nephpearls #RKDSummit #NephSky 👉🏼 pubmed.ncbi.nlm.nih.gov/42628835/26 Sep 2026 18:28 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mwgw23swjs23https://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mwgvkswhic23Microscopic hematuria as a risk factor for #IgAN progression: considering this biomarker in selecting and monitoring patients ca. 2023 #Nephpearls #RKDSummit #NephSky 👉🏼 pubmed.ncbi.nlm.nih.gov/38053974/26 Sep 2026 18:20 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mwgvkswhic23https://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mwgrtkoepk2aTargeting B cells in immune-mediated kidney diseases: conclusions from @kdigo.org Controversies Conference ca. 2026 #Nephpearls #RKDSummit #NephSky 👉🏼 pubmed.ncbi.nlm.nih.gov/42034308/26 Sep 2026 17:13 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mwgrtkoepk2ahttps://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mwcumvcfls27Colloids vs Crystalloids #Nephpearls #AKIinICU #NephSky 👉 https://shop.lww.com/Handbook-of-Critical-Care-Nephrology/p/9781975144098?srsltid=AU7gw4XDBfnpCt_OxDYvUwIZOsI0a5iAQ8ENHYOz3WBiWcw-znlp5GM_25 Sep 2026 03:52 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mwcumvcfls27https://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3mv2qpejmks26Thank you for the kind words and the wonderful hospitality! It was an absolute honor to present at the Renal Research Forum and engage with such a fantastic group of colleagues at Mayo Clinic 🙏 #NephSky [contains quote post or other embedded content]09 Sep 2026 04:55 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3mv2qpejmks26https://connect.medsky.network/profile/edgarvlermamd.medsky.network/post/3murw3q6pzk25Kidney Health Guidance on Cardiovascular-Kidney-Metabolic (CKM) Syndrome ca. 2026 from @asnpublications.bsky.social #Nephpearls #NephSky #Cardiorenal 👉 pubmed.ncbi.nlm.nih.gov/42684397/05 Sep 2026 16:38 +0000at://did:plc:c4w7wylurewxcengmxandlcu/app.bsky.feed.post/3murw3q6pzk25